产品名称
Integrin alpha 2 (19O18) Rabbit Monoclonal Antibody
别名
BR; CD 49b; CD49 antigen like family member B; Collagen receptor; GPIa; HPA5; ITGA2; Platelet glycoprotein GPIa; VLA 2 alpha chain;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P17301
稀释度
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:100 FC 1:100
注意事项
Integrin alpha 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Membrane; Single-pass type I membrane protein.
功能
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
