产品名称
IL1RA (3V4) Rabbit Monoclonal Antibody
别名
DIRA; ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); Interleukin-1 receptor antagonist protein; IRAP; Type II interleukin 1 receptor antagonist;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P18510
免疫原
A synthetic peptide of human IL1RA
注意事项
IL1RA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
The intracellular form of IL1RN is predominantly expressed in epithelial cells
细胞定位
[Isoform 1]: Secreted. [Isoform 3]: Cytoplasm.
功能
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
