产品名称
Cytokeratin 18 (9H8) Rabbit Monoclonal Antibody
别名
type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; Keratin-18; KRT18; CYK18; PIG46; KRT 18; CK18; Keratin 18;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P05783
稀释度
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:60
注意事项
Cytokeratin 18 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
细胞定位
Cytoplasm, perinuclear region. Nucleus, nucleolus
功能
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
