产品名称
AMZ2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51321
Human Swissprot No.
Q86W34
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86W34/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13929
Mouse Swissprot No.
Q400C8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q400C8
Rat Gene Link
https://www.uniprot.org/uniprot/360650
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q400C7
免疫原
Synthesized peptide derived from human AMZ2 AA range: 99-149
特异性
This antibody detects endogenous levels of AMZ2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS).
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,enzyme regulation:Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.,function:Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.,sequence caution:Translated as Gly.,similarity:Belongs to the peptidase archaemetzincin family.,tissue specificity:Predominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
