产品名称
MUC16 (16A14) Rabbit Monoclonal Antibody
别名
Cancer antigen 125; CA125; CA125 ovarian cancer; MUC 16; Mucin16; Ovarian cancer related tumor marker CA125;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q8WXI7
稀释度
WB 1:5000~1:20000 ICC/IF 1:50~1:200 FC 1:100
注意事项
MUC16 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas
细胞定位
Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain
功能
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
