产品名称
MEKK2 (9D14) Rabbit Monoclonal Antibody
别名
MAP3K2; MAP/ERK kinase kinase 2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9Y2U5
免疫原
A synthetic peptide of human MEKK2
稀释度
WB: 1:2000-1:10000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20 IP: 1:20
注意事项
MEKK2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm. Nucleus. Note=Upon EGF stimulation, translocates into the nucleus
功能
Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and- run dynamics.
