产品名称
NSD3 (15Z13) Rabbit Monoclonal Antibody
别名
Wolf Hirschhorn syndrome candidate 1 like 1; WHSC1L1; NSD3; pp14328; Histone-lysine N-methyltransferase NSD3; Protein whistle;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9BZ95
稀释度
WB 1:1000~1:5000 FC 1:30
注意事项
NSD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung
细胞定位
Nucleus. Chromosome.
功能
Histone methyltransferase. Preferentially dimethylates 'Lys- 4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
