产品名称
WASF2 (18L2) Rabbit Monoclonal Antibody
别名
Wiskott-Aldrich syndrome protein family member 2WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2; WASF2;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9Y6W5
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
WASF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.
细胞定位
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Basolateral cell membrane. Note=At the interface between the lamellipodial actin meshwork and the membrane.
功能
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
