产品名称
LHX4 Rabbit Polyclonal Antibody
蛋白名称
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q969G2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q969G2/entry
Mouse Swissprot No.
P53776
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P53776
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
LHX4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010],
功能
disease:A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1.,disease:Defects in LHX4 are the cause of Machinis syndrome [MIM:606606]. It is characterized by short stature, pituitary and cerebellar defects, and small sella turcica.,function:May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
