产品名称
CD168 (2C15) Rabbit Monoclonal Antibody
别名
Hyaluronan mediated motility receptor; Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; CD168; HMMR; IHABP; RHAMM;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O75330
免疫原
A synthetic peptide of human CD168
稀释度
WB: 1:1000-1:5000 IHC: 1:20-1:100 IP: 1:20-1:50
注意事项
CD168 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in testis (PubMed:22965910). Expressed in the breast (PubMed:8890751).
细胞定位
Cell surface {ECO:0000250|UniProtKB:Q00547}. Cytoplasm {ECO:0000250|UniProtKB:Q00547}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q00547}
功能
Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
