RM4648

IKB beta (7N9) Rabbit Monoclonal Antibody

I-kappa-B-beta; IkB-B; IkB-beta; IKBB; NF-kappa-BIB; NFKBIB; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP;

Affinity-chromatography

常规抗体

NFKBIB

IKBB, TRIP9

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

4793

Q15653

A synthetic peptide of human IKB beta

WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 IP: 1:20

48kDa

38kDa

Rabbit IgG

IKB beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in all tissues examined.

Cytoplasm. Nucleus.

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

现货