产品名称
IKB beta (7N9) Rabbit Monoclonal Antibody
别名
I-kappa-B-beta; IkB-B; IkB-beta; IKBB; NF-kappa-BIB; NFKBIB; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15653
免疫原
A synthetic peptide of human IKB beta
注意事项
IKB beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in all tissues examined.
功能
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.