RM4611

PLC gamma 1 (11C1) Rabbit Monoclonal Antibody

PLC-148; PLC-II; PLC-gamma1; PLC1; PLCG-1; Phospholipase C-gamma-1;

Affinity-chromatography

常规抗体

PLCG1

PLC1

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

5335

P19174

WB 1:1000~1:5000 ICC/IF 1:50~1:200 IP 1:50

149kDa

Rabbit IgG

PLC gamma 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (PubMed:17229814).

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