产品名称
GOLPH2 (7R10) Rabbit Monoclonal Antibody
别名
GOLPH2; GP73; GOLM1; Golgi protein 73kD; C9orf155;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q8NBJ4
稀释度
WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
GOLPH2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis) Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant- cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
细胞定位
Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption
功能
Unknown. Cellular response protein to viral infection.
