RM4549

Cytokeratin 14 (18K1) Rabbit Monoclonal Antibody

Keratin type I cytoskeletal 14; Cytokeratin-14; CK-14; CK14;

Affinity-chromatography

常规抗体

KRT14

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

3861

P02533

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

52kDa

Rabbit IgG

Cytokeratin 14 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in the corneal epithelium (at protein level) (PubMed:26758872). Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair (PubMed:9457912). Found in keratinocytes surrounding the club hair during telogen (PubMed:9457912).

Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern

The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

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