产品名称
DYNLL1 (5C17) Rabbit Monoclonal Antibody
别名
DLC8; DLC1; DNCL1; DYNLL1; HDLC1; LC8a; PIN;
纯度
Affinity-chromatography
蛋白名称
DLC1, DNCL1, DNCLC1, HDLC1
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P63167
免疫原
A synthetic peptide of human DYNLL1
稀释度
WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20-1:50 FC: 1:200 IP: 1:20
注意事项
DYNLL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitous (PubMed:8628263). Expressed in testis (PubMed:22965910).
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Note=Upon induction of apoptosis translocates together with BCL2L11 to mitochondria
功能
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.
