产品名称
GRM5 (6R13) Rabbit Monoclonal Antibody
别名
GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P41594
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
GRM5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Multi-pass membrane protein
功能
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
