产品名称
PGK1 (4F5) Rabbit Monoclonal Antibody
别名
MGC117307; MGC142128; MGC8947; MIG10; PGKA; PGK1; PRP2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P00558
免疫原
A synthetic peptide of human PGK1
稀释度
WB: 1:1000 ICC/IF: 1:50 FC: 1:20
注意事项
PGK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men
功能
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate (PubMed:
30323285, PubMed:
7391028). In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:
2324090). May play a role in sperm motility (PubMed:
26677959).
