产品名称
VPREB Rabbit Polyclonal Antibody
蛋白名称
Immunoglobulin iota chain (CD179 antigen-like family member A) (Protein VPreB1) (V(pre)B protein) (VpreB protein) (CD antigen CD179a)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P12018
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P12018/entry
免疫原
Synthesized peptide derived from part region of human protein
特异性
VPREB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
组织表达
Only expressed by pre-B-cells.
细胞定位
Endoplasmic reticulum .
功能
function:Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates ig gene rearrangements in the early steps of B-cell differentiation.,similarity:Belongs to the immunoglobulin superfamily.,subunit:Associates non-covalently with IGLL1.,tissue specificity:Only expressed by pre-B-cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
