产品名称
HMCS1 Rabbit Polyclonal Antibody
蛋白名称
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q01581
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q01581/entry
Mouse Swissprot No.
Q8JZK9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8JZK9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P17425
免疫原
Synthesized peptide derived from part region of human protein
特异性
HMCS1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,
组织表达
Brain,Epithelium,Fetal adrenal gland,Fibroblast,Liver,Lung,
信号通路
Synthesis and degradation of ketone bodies;Valine; leucine and isoleucine degradation;Butanoate metabolism;Terpenoid backbone biosynthesis;
功能
catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.