产品名称
							
							
								 HMCS1 Rabbit Polyclonal Antibody							
						 
												
												
												
							
								蛋白名称
							
							
								Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)							
						 
												
												
												
												
							
								存储缓冲液
							
							
								Liquid in PBS containing 50% glycerol,  and 0.02% New type preservative N.							
						 
												
												
							
								Human Swissprot No.
							
							
								Q01581							
						 
												
							
								Human Swissprot Link
							
							
								https://www.uniprot.org/uniprotkb/Q01581/entry							
						 
												
							
								Mouse Swissprot No.
							
							
								Q8JZK9							
						 
												
							
								Mouse Swissprot Link
							
							
								http://www.uniprot.org/uniprot/Q8JZK9							
						 
												
												
							
								Rat Swissprot Link
							
							
								http://www.uniprot.org/uniprot/O54941P17425							
						 
												
							
								免疫原
							
							
								Synthesized peptide derived from part region of human protein							
						 
												
							
								特异性
							
							
								HMCS1 Polyclonal Antibody detects endogenous levels of protein.							
						 
												
							
								稀释度
							
							
								WB 1:500-2000 ELISA 1:5000-20000							
						 
												
												
												
							
								宿主
							
							
								Polyclonal, Rabbit,IgG							
						 
												
							
								背景介绍
							
							
								catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,							
						 
												
							
								组织表达
							
							
								 Brain,Epithelium,Fetal adrenal gland,Fibroblast,Liver,Lung,							
						 
												
												
							
								信号通路
							
							
								Synthesis and degradation of ketone bodies;Valine; leucine and isoleucine degradation;Butanoate metabolism;Terpenoid backbone biosynthesis;							
						 
												
							
								功能
							
							
								catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,							
						 
												
												
							
								纯化
							
							
								The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.