RM4434

Stathmin 1 (10E8) Rabbit Monoclonal Antibody

LAG; LAP18; Leukemia-associated gene protein; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp17; pp19; PR22; Pr22 protein; Prosolin;SMN;Stathmin1;STMN1;

Affinity-chromatography

常规抗体

STMN1

C1orf215, LAP18, OP18

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

3925

P16949

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1: 50 FC 1:50

17kDa

Rabbit IgG

Stathmin 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Cytoplasm, cytoskeleton.

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).

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