产品名称
MCSF (11G12) Rabbit Monoclonal Antibody
别名
CSF1; Csfm; MCSF; MGC31930; Macrophage colony stimulating factor;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P09603
免疫原
A synthetic peptide of human M-CSF
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:20
参考分子量
According to the recombinant protein
注意事项
MCSF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Single-pass type I membrane protein
功能
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
