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SCARB1 (15Q10) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM4367
产品名称
SCARB1 (15Q10) Rabbit Monoclonal Antibody
别名
CD36L1; CLA-1; CLA1; MGC138242; SR-BI; SRB1; Scavenging Receptor SR-BI; Collagen type I receptor;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
SCARB1
蛋白名称
CD36L1, CLA1
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Gene ID
949
Human Swissprot No.
Q8WTV0
免疫原
A synthetic peptide of human Scavenging Receptor SR-BI
稀释度
WB: 1:1000 IHC: 1:100
参考分子量
80kDa
预测分子量
61kDa
同种型
Rabbit IgG
注意事项
SCARB1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed.
细胞定位
Cell membrane; Multi-pass membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:Q61009}; Multi-pass membrane protein Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae
功能
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).
期货
现货

Western blot analysis of SCARB1 expression in (1) Human fetal liver lysate; (2) Mouse liver lysate.

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