产品名称
NKX22 Rabbit Polyclonal Antibody
蛋白名称
Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95096
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95096/entry
Mouse Swissprot No.
P42586
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P42586
免疫原
Synthesized peptide derived from part region of human protein
特异性
NKX22 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008],
信号通路
Maturity onset diabetes of the young;
功能
domain:The homeodomain is essential for interaction with OLIG2.,function:May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.,similarity:Belongs to the NK-2 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with OLIG2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
