产品名称
MMP1 (7R3) Rabbit Monoclonal Antibody
别名
MMP1;CLG;CLGN; Fibroblast collagenase; Matrix metalloprotease 1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P03956
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC 1:50~1:200 FC 1:50
注意事项
MMP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Secreted, extracellular space, extracellular matrix
功能
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X (PubMed:
2557822, PubMed:
2153297, PubMed:
1645757). In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity (PubMed:
16807369).
