产品名称
B Raf (9L5) Rabbit Monoclonal Antibody
别名
B-RAF; p94; NS7; B-Raf proto-oncogene serine/threonine-protein kinase;BRAF;BRAF1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P15056
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50
注意事项
B Raf Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
功能
Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:
21441910, PubMed:
29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:
1508179).
