产品名称
TCF3 (6X16) Rabbit Monoclonal Antibody
别名
Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9HCS4
注意事项
TCF3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium
功能
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.
