产品名称
Paxillin (5M15) Rabbit Monoclonal Antibody
别名
Paired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P49023
免疫原
A synthetic peptide of human Paxillin
稀释度
WB: 1:2000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20 IP: 1:50
注意事项
Paxillin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q8VI36}. Note=Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389) {ECO:0000250, ECO:0000269|PubMed:23128389}
功能
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
