产品名称
Thrombomodulin (14C15) Rabbit Monoclonal Antibody
别名
CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P07204
注意事项
Thrombomodulin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Endothelial cells are unique in synthesizing thrombomodulin
细胞定位
Membrane; Single-pass type I membrane protein.
功能
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
