产品名称
LDL Receptor (14L10) Rabbit Monoclonal Antibody
别名
FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P01130
稀释度
WB 1:1000~1:2000 IHC 1:100~1:500
注意事项
LDL Receptor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P01131}. Membrane, clathrin-coated pit. Golgi apparatus. Early endosome. Late endosome. Lysosome Note=Rapidly endocytosed upon ligand binding
功能
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
