产品名称
CD11c (1D8) Rabbit Monoclonal Antibody
别名
p150/95 integrin alpha chain; Leu M5; SLEB6; ITGAX; CD11c; p150;Myeloid membrane antigen alpha subunit; Leukocyte surface antigen p150 95 alpha subunit; Integrin alpha-X;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P20702
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
注意事项
CD11c Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Predominantly expressed in monocytes and granulocytes
细胞定位
Membrane; Single-pass type I membrane protein.
功能
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
