产品名称
NKX22 Rabbit Polyclonal Antibody
蛋白名称
Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95096
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95096/entry
Mouse Swissprot No.
P42586
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P42586
免疫原
Synthesized peptide derived from part region of human protein
特异性
NKX22 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008],
信号通路
Maturity onset diabetes of the young;
功能
domain:The homeodomain is essential for interaction with OLIG2.,function:May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.,similarity:Belongs to the NK-2 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with OLIG2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
