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MMP9 (16P9) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM4223
产品名称
MMP9 (16P9) Rabbit Monoclonal Antibody
别名
MMP9; GELB; CLG4B; Matrix Metalloproteinase 9; MANDP2; Gelatinase beta;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
MMP9
蛋白名称
CLG4B
推荐应用
WB
反应种属
Human,Rat
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
4318
Human Swissprot No.
P14780
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
预测分子量
78kDa
同种型
Rabbit IgG
注意事项
MMP9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in neutrophils (at protein level) (PubMed:7683678). Produced by normal alveolar macrophages and granulocytes.
细胞定位
Secreted, extracellular space, extracellular matrix
功能
Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed:2551898, PubMed:1480034, PubMed:12879005). Could play a role in bone osteoclastic resorption (By similarity). Cleaves KiSS1 at a Gly-|-Leu bond (PubMed:12879005). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:32883094). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N- terminal one quarter fragments (PubMed:1480034). Degrades fibronectin but not laminin or Pz-peptide.
期货
现货

Western blot analysis of MMP9 expression in (1)Rat kidney tissue lysate;(2)Rat lung tissue lysate.

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