产品名称
MCL1 (18O13) Rabbit Monoclonal Antibody
别名
Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; Bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1; mcl1/EAT; MCL1L; MCL1S;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q07820
免疫原
A synthetic peptide of human MCL1
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 FC: 1:50 IP: 1:20
注意事项
MCL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm Note=Cytoplasmic, associated with mitochondria
功能
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
