RM4212

PSMA (14M3) Rabbit Monoclonal Antibody

FGCP;FOLH 1;GCP 2;GCPII;mGCP;NAALADase I;PSM;PSMA

Affinity-chromatography

常规抗体

FOLH1

FOLH, NAALAD1, PSM, PSMA

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

2346

Q04609

A synthetic peptide of human PSMA

WB: 1:1000

100kDa

84kDa

Rabbit IgG

PSMA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Highly expressed in prostate epithelium. Detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon and brain (at protein level). Detected in the small intestine, brain, kidney, liver, spleen, colon, trachea, spinal cord and the capillary endothelium of a variety of tumors. Expressed specifically in jejunum brush border membranes. In the brain, highly expressed in the ventral striatum and brain stem. Also expressed in fetal liver and kidney Isoform PSMA' is the most abundant form in normal prostate. Isoform PSMA-1 is the most abundant form in primary prostate tumors. Isoform PSMA-3 is also found in normal prostate as well as in brain and liver Isoform PSMA-9 is specifically expressed in prostate cancer

Cell membrane; Single-pass type II membrane protein

Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

现货