RM4221

S100B (6D3) Rabbit Monoclonal Antibody

S100B;NEF;S100;S100beta ;

Affinity-chromatography

常规抗体

S100B

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

6285

P04271

A synthetic peptide of human S100B

WB 1:1000

11kDa

11kDa

Rabbit IgG

S100B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues

Cytoplasm. Nucleus

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

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