RM4207

TRAM2 (17O9) Rabbit Monoclonal Antibody

KIAA0057;TRAM like protein;Tram2;Translocating chain associating membrane protein 2;Translocation associated membrane protein 2

Affinity-chromatography

常规抗体

TRAM2

KIAA0057

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

9697

Q15035

WB 1:500~1:2000

43kDa

Rabbit IgG

TRAM2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Membrane; Multi-pass membrane protein

Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293).

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