产品名称
HXB1 Rabbit Polyclonal Antibody
蛋白名称
Homeobox protein Hox-B1 (Homeobox protein Hox-2I)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P14653
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P14653/entry
Mouse Swissprot No.
P17919
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P17919
免疫原
Synthesized peptide derived from part region of human protein
特异性
HXB1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008],
功能
function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.,polymorphism:The two common alleles; HOX1B*A and HOX1B*B have a frequency of 78.8% and 21.2% respectively.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.