产品名称
C9 (12U11) Rabbit Monoclonal Antibody
别名
Complement component C9; Comple Complement component C9bment component C9a;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P02748
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
注意事项
C9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Plasma (at protein level).
细胞定位
Secreted. Target cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore
功能
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:
9634479, PubMed:
9212048, PubMed:
26841934). C9 is the pore-forming subunit of the MAC (PubMed:
4055801, PubMed:
26841934, PubMed:
30111885).
