产品名称
CD20 (18I8) Rabbit Monoclonal Antibody
别名
B1; S7; Bp35; CD20; MS4A2; LEU-16; MS4A1
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P11836
免疫原
A synthetic peptide of human CD20
稀释度
WB: 1:2000 IHC: 1:100 IP: 1:20
注意事项
CD20 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed on B-cells.
细胞定位
Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. Note=Constitutively associated with membrane rafts.
功能
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:
3925015, PubMed:
7684739, PubMed:
12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:
7684739, PubMed:
12920111, PubMed:
18474602).
