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c-Myc (9U18) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM4176
产品名称
c-Myc (9U18) Rabbit Monoclonal Antibody
别名
c-Myc; Class E basic helix-loop-helix protein 39; MRTL; MYC; Myc proto-oncogene protein; v-myc;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
MYC
蛋白名称
BHLHE39
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Gene ID
4609
Human Swissprot No.
P01106
免疫原
A synthetic peptide of human c-Myc
稀释度
WB: 1:2000 IHC: 1:200 ICC/IF: 1:100 FC: 1:100 IP: 1:50
参考分子量
57-65kDa
预测分子量
49kDa
同种型
Rabbit IgG
注意事项
c-Myc Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus, nucleoplasm. Nucleus, nucleolus
功能
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).
期货
现货

Western blot analysis of c-Myc expression in (1) Jurkat cell lysate;(2) K562 cell lysate.

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