RM4171

CCL19 (11F3) Rabbit Monoclonal Antibody

CCL 19;CK beta 11;EBI 1 ligand chemokine;ELC;Exodus3;;MIP3 beta;SCYA 19;SCYA19

Affinity-chromatography

常规抗体

CCL19

ELC, MIP3B, SCYA19

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

6363

Q99731

WB 1:500~1:2000

11kDa

Rabbit IgG

CCL19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach

Secreted.

May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta- arrestin (ARRB1/2) to ACKR4.

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