产品名称
Plectin (16X18) Rabbit Monoclonal Antibody
别名
EBS1; EBSO; HD1; Hemidesmosomal protein 1; PCN; pleC; PLEC1 ;Plectin 1; Plectin 6; Plectin; PLTN
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q15149
稀释度
WB 1:1000~1:2000 IHC 1:50~1:100 IP 1:30
注意事项
Plectin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Widely expressed with highest levels in muscle, heart, placenta and spinal cord
细胞定位
Cytoplasm, cytoskeleton. Cell junction, hemidesmosome
功能
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
