产品名称
Heme Oxygenase 1 (1F4) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P09601
免疫原
A synthetic peptide of human Heme Oxygenase 1
稀释度
WB: 1:1000-1:5000 ICC/IF: 1:100-1:200 FC: 1:100-1:200 IP: 1:20
注意事项
Heme Oxygenase 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level)
细胞定位
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
功能
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
