产品名称
ENO1 (9I18) Rabbit Monoclonal Antibody
别名
ENO1;ENO1L1;MBP-1;MPB1;NNE;PPH;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P06733
免疫原
A synthetic peptide of human ENO1
稀释度
WB: 1:1000 IHC: 1:500-1:1000 ICC/IF: 1:200-1:500 FC: 1:200-1:500 IP: 1:20
注意事项
ENO1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons
细胞定位
Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line
功能
Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate (PubMed:
29775581, PubMed:
1369209). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:
2005901, PubMed:
10802057, PubMed:
12666133, PubMed:
29775581). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (PubMed:
12666133). Stimulates immunoglobulin production (PubMed:
1369209).
