产品名称
Sonic Hedgehog (15Y5) Rabbit Monoclonal Antibody
别名
TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; Sonic Hedgehog;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15465
免疫原
A synthetic peptide of human Sonic Hedgehog
稀释度
WB: 1:1000-1:5000 IHC: 1:500-1:2000 ICC/IF: 1:200-1:500 FC: 1:20
注意事项
Sonic Hedgehog Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane.
功能
[Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).
