产品名称
Sonic Hedgehog (15Y5) Rabbit Monoclonal Antibody
别名
TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; Sonic Hedgehog;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15465
免疫原
A synthetic peptide of human Sonic Hedgehog
注意事项
Sonic Hedgehog Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane.
功能
[Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).