产品名称
Cytokeratin 18 (8W18) Rabbit Monoclonal Antibody
别名
Keratin-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; K1C18; keratin 18; KRT18; CK-18;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P05783
免疫原
Recombinant protein of human Cytokeratin 18
稀释度
WB: 1:2000 IHC: 1:20 ICC/IF: 1:20-1:100 FC: 1:20
注意事项
Cytokeratin 18 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
细胞定位
Cytoplasm, perinuclear region. Nucleus, nucleolus
功能
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
