产品名称
MKLP1 (3O6) Rabbit Monoclonal Antibody
别名
CHO 1;CHO1;KIF 23;KIF23;;KNS L5;KNSL 5;KNSL5;Mitotic kinesin like 1;Mitotic kinesin like protein 1;MKLP 1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q02241
免疫原
A synthetic peptide of human MKLP1
稀释度
WB: 1:1000 IHC: 1:50 ICC/IF: 1:50
注意事项
MKLP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis
功能
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
