产品名称
MKLP1 (3O6) Rabbit Monoclonal Antibody
别名
CHO 1;CHO1;KIF 23;KIF23;;KNS L5;KNSL 5;KNSL5;Mitotic kinesin like 1;Mitotic kinesin like protein 1;MKLP 1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q02241
免疫原
A synthetic peptide of human MKLP1
注意事项
MKLP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis
功能
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
